- Myristoyl-CoA 11-(E) desaturase
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myristoyl-CoA 11-(E) desaturase Identifiers EC number 1.14.99.31 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a myristoyl-CoA 11-(E) desaturase (EC 1.14.99.31) is an enzyme that catalyzes the chemical reaction
- myristoyl-CoA + NAD(P)H + H+ + O2
(E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O
The 5 substrates of this enzyme are myristoyl-CoA, NADH, NADPH, H+, and O2, whereas its 4 products are (E)-11-tetradecenoyl-CoA, NAD+, NADP+, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating].
References
- Navaro I, Font I, Fabrias G and Camps F (1997). "Stereospecificity of the (E)- and (Z)-11 myristoyl desaturases in the biosynthesis of Spodoptera littoralis sex pheromone". J. Am. Chem. Soc. 119 (46): 11335–11336. doi:10.1021/ja972577v.
This EC 1.14 enzyme-related article is a stub. You can help Wikipedia by expanding it. - myristoyl-CoA + NAD(P)H + H+ + O2
