- Dibenzothiophene dihydrodiol dehydrogenase
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dibenzothiophene dihydrodiol dehydrogenase Identifiers EC number 1.3.1.60 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a dibenzothiophene dihydrodiol dehydrogenase (EC 1.3.1.60) is an enzyme that catalyzes the chemical reaction
- cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+
1,2-dihydroxydibenzothiophene + NADH + H+
Thus, the two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and NAD+, whereas its 3 products are 1,2-dihydroxydibenzothiophene, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase.
References
- Laborde AL, Gibson DT (1977). "Metabolism of dibenzothiophene by a Beijerinckia species". Appl. Environ. Microbiol. 34 (6): 783–90. PMC 242748. PMID 596875. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=242748.
- Denome SA, Stanley DC, Olson ES, Young KD (1993). "Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway". J. Bacteriol. 175 (21): 6890–901. PMC 206814. PMID 8226631. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=206814.
This EC 1.3 enzyme-related article is a stub. You can help Wikipedia by expanding it. - cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+
