- Cis-dihydroethylcatechol dehydrogenase
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cis-dihydroethylcatechol dehydrogenase Identifiers EC number 1.3.1.66 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cis-dihydroethylcatechol dehydrogenase (EC 1.3.1.66) is an enzyme that catalyzes the chemical reaction
- cis-1,2-dihydro-3-ethylcatechol + NAD+ 3-ethylcatechol + NADH + H+
Thus, the two substrates of this enzyme are cis-1,2-dihydro-3-ethylcatechol and NAD+, whereas its 3 products are 3-ethylcatechol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase. This enzyme participates in ethylbenzene degradation.
References
- Gibson DT, Gschwendt B, Yeh WK, Kobal VM (1973). "Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida". Biochemistry. 12 (8): 1520–8. doi:10.1021/bi00732a008. PMID 4699984.
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