Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase

cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Identifiers
EC number	1.3.1.56
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC 1.3.1.56) is an enzyme that catalyzes the chemical reaction

cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD⁺ $\rightleftharpoons$ biphenyl-2,3-diol + NADH + H⁺

Thus, the two substrates of this enzyme are cis-3-phenylcyclohexa-3,5-diene-1,2-diol and NAD⁺, whereas its 3 products are biphenyl-2,3-diol, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase. This enzyme is also called 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase. This enzyme participates in biphenyl degradation.

References

• Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D (1996). "Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB)". Appl. Environ. Microbiol. 62 (8): 2710–5. PMC 168055. PMID 8702262. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=168055. 
• Takagi M, Yano K (1994). "Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls". Biochem. Biophys. Res. Commun. 202 (2): 850–6. doi:10.1006/bbrc.1994.2008. PMID 8048958. 
• Hofer B, Eltis LD, Dowling DN, Timmis KN (1993). "Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation". Gene. 130 (1): 47–55. doi:10.1016/0378-1119(93)90345-4. PMID 8344527. 

This EC 1.3 enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: EC 1.3 stubs EC 1.3.1 NADH-dependent enzymes Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем написать курсовую Forever Reeling (song) Kubrat Pulev Look at other dictionaries: List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”