- Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
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cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase Identifiers EC number 1.3.1.29 CAS number 53986-49-5 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase (EC 1.3.1.29) is an enzyme that catalyzes the chemical reaction
- cis-1,2-dihydronaphthalene-1,2-diol + NAD+ naphthalene-1,2-diol + NADH + H+
Thus, the two substrates of this enzyme are cis-1,2-dihydronaphthalene-1,2-diol and NAD+, whereas its 3 products are naphthalene-1,2-diol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase. Other names in common use include (+)-cis-naphthalene dihydrodiol dehydrogenase, naphthalene dihydrodiol dehydrogenase, and cis-dihydrodiol naphthalene dehydrogenase. This enzyme participates in 1- and 2-methylnaphthalene degradation and naphthalene and anthracene degradation.
References
- Patel TR, Gibson DT (1974). "Purification and properties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida". J. Bacteriol. 119 (3): 879–88. PMC 245694. PMID 4369091. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=245694.
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