All-trans-retinol 13,14-reductase

All-trans-retinol 13,14-reductase

In enzymology, an all-trans-retinol 13,14-reductase (EC number|1.3.99.23) is an enzyme that catalyzes the chemical reaction

:all-trans-13,14-dihydroretinol + acceptor ightleftharpoons all-trans-retinol + reduced acceptor

Thus, the two substrates of this enzyme are all-trans-13,14-dihydroretinol and acceptor, whereas its two products are all-trans-retinol and reduced acceptor. Under physiological conditions the reaction proceeds in the opposite direction catalyzing the saturation of the 13-14 double bond of all-trans-retinol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase. Other names in common use include retinol saturase, RetSat, (13,14)-all-trans-retinol saturase, and all-trans-retinol:all-trans-13,14-dihydroretinol saturase.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|418767-56-3."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Retinol dehydrogenase — In enzymology, a retinol dehydrogenase (EC number|1.1.1.105) is an enzyme that catalyzes the chemical reaction:retinol + NAD+ ightleftharpoons retinal + NADH + H+Thus, the two substrates of this enzyme are retinol and NAD+, whereas its 3 products …   Wikipedia

  • RETSAT — Retinol saturase (all trans retinol 13,14 reductase), also known as RETSAT, is a human gene.cite web | title = Entrez Gene: RETSAT retinol saturase (all trans retinol 13,14 reductase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • RDH8 — Retinol dehydrogenase 8 (all trans), also known as RDH8, is a human gene.cite web | title = Entrez Gene: RDH8 retinol dehydrogenase 8 (all trans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=50700|… …   Wikipedia

  • RDH11 — Retinol dehydrogenase 11 (all trans/9 cis/11 cis), also known as RDH11, is a human gene.cite web | title = Entrez Gene: RDH11 retinol dehydrogenase 11 (all trans/9 cis/11 cis)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • RDH14 — Retinol dehydrogenase 14 (all trans/9 cis/11 cis), also known as RDH14, is a human gene.cite web | title = Entrez Gene: RDH14 retinol dehydrogenase 14 (all trans/9 cis/11 cis)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • retinaldehyde — Retinol oxidized to a terminal aldehyde; retinal; a carotene released (as all trans retinal) in the bleaching of rhodopsin by light and the dissociation of opsin in the vision cycle. SYN: retinene 1 …   Medical dictionary

  • Tretinoin — Systematic (IUPAC) name retinoic acid …   Wikipedia

  • DHRS3 — Dehydrogenase/reductase (SDR family) member 3 Identifiers Symbols DHRS3; RDH17; Rsdr1; SDR1; SDR16C1; retSDR1 External IDs …   Wikipedia

  • retinal — 1. Relating to the retina. 2. Retinaldehyde; most commonly referring to the all trans form. r. dehydrogenase an oxidoreductase catalyzing the interconversion of retinaldehyde and NAD+ to retinoic acid and NADH …   Medical dictionary

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”