Theobromine synthase

In enzymology, a theobromine synthase (EC number|2.1.1.159) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + 7-methylxanthine $ightleftharpoons$ S-adenosyl-L-homocysteine + 3,7-dimethylxanthine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 7-methylxanthine, whereas its two products are S-adenosylhomocysteine and 3,7-dimethylxanthine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:7-methylxanthine N3-methyltransferase. Other names in common use include monomethylxanthine methyltransferase, MXMT, CTS1, CTS2, and S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase.

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