Phosphatidylethanolamine N-methyltransferase
- Phosphatidylethanolamine N-methyltransferase
protein
name=phosphatidylethanolamine N-methyltransferase
caption=
width=
HGNCid=8830
Symbol=PEMT
AltSymbols=
EntrezGene=10400
OMIM=
RefSeq=NM_007169
UniProt=
PDB=
ECnumber=2.1.1.17
Chromosome=17
Arm=p
Band=11.2
LocusSupplementaryData=In enzymology, a phosphatidylethanolamine N-methyltransferase (EC number|2.1.1.17) is an enzyme that catalyzes the chemical reaction
:S-adenosyl-L-methionine + phosphatidylethanolamine S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
Thus, the two substrates of this enzyme are S-adenosyl methionine and phosphatidylethanolamine, whereas its two products are S-adenosylhomocysteine and phosphatidyl-N-methylethanolamine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase. Other names in common use include PEMT, LMTase, lipid methyl transferase, phosphatidylethanolamine methyltransferase, phosphatidylethanolamine-N-methylase, and phosphatidylethanolamine-S-adenosylmethionine methyltransferase. This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|37256-91-0."
Gene Ontology (GO) codes
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