Caffeate O-methyltransferase

In enzymology, a caffeate O-methyltransferase (EC number|2.1.1.68) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate $ightleftharpoons$ S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate

Thus, the two substrates of this enzyme are S-adenosyl methionine and 3,4-dihydroxy-trans-cinnamate, whereas its two products are S-adenosylhomocysteine and 3-methoxy-4-hydroxy-trans-cinnamate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase. Other names in common use include caffeate methyltransferase, caffeate 3-O-methyltransferase, and S-adenosyl-L-methionine:caffeic acid-O-methyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1KYW and PDB link|1KYZ.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|50936-45-3."

Gene Ontology (GO) codes