2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

In enzymology, a 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase (EC number|1.1.1.126) is an enzyme that catalyzes the chemical reaction

:2-dehydro-3-deoxy-D-gluconate + NADP⁺ $$ightleftharpoons (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H⁺

Thus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NADP⁺, whereas its 3 products are (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase. Other names in common use include 2-keto-3-deoxy-D-gluconate dehydrogenase, and 2-keto-3-deoxygluconate dehydrogenase.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37250-55-8."

Gene Ontology (GO) codes