L-threonine 3-dehydrogenase
- L-threonine 3-dehydrogenase
In enzymology, a L-threonine 3-dehydrogenase (EC number|1.1.1.103) is an enzyme that catalyzes the chemical reaction
:L-threonine + NAD+ L-2-amino-3-oxobutanoate + NADH + H+
Thus, the two substrates of this enzyme are L-threonine and NAD+, whereas its 3 products are L-2-amino-3-oxobutanoate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-threonine:NAD+ oxidoreductase. Other names in common use include L-threonine dehydrogenase, threonine 3-dehydrogenase, and threonine dehydrogenase. This enzyme participates in glycine, serine and threonine metabolism.
tructural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2D8A, PDB link|2DFV, and PDB link|2DQ4.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9067-99-6."
Gene Ontology (GO) codes
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