Glycerol dehydrogenase

In enzymology, a glycerol dehydrogenase (EC number|1.1.1.6) is an enzyme that catalyzes the chemical reaction:

:glycerol + NAD⁺ $ightleftharpoons$ glycerone + NADH + H⁺

Thus, the two substrates of this enzyme are glycerol and NAD⁺, whereas its three products are glycerone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycerol:NAD+ 2-oxidoreductase. Other names in common use include glycerin dehydrogenase, and NAD+-linked glycerol dehydrogenase. This enzyme participates in glycerolipid metabolism.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1JPU, PDB link|1JQ5, PDB link|1JQA, and PDB link|1TA9.

ee also

* Glycerol dehydrogenase (NADP+)
* Glycerol dehydrogenase (acceptor)

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9028-14-2."

Gene Ontology (GO) codes