TRPM7

Transient receptor potential cation channel, subfamily M, member 7, also known as TRPM7, is a human gene.

PBB_Summary
section_title =
summary_text = TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants. [supplied by OMIM] [cite web | title = Entrez Gene: TRPM7 transient receptor potential cation channel, subfamily M, member 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54822| accessdate = ]

ee also

* TRPM

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Chubanov V, Gudermann T, Schlingmann KP |title=Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis. |journal=Pflugers Arch. |volume=451 |issue= 1 |pages= 228–34 |year= 2006 |pmid= 16075242 |doi= 10.1007/s00424-005-1470-y
*cite journal | author=Clapham DE, Julius D, Montell C, Schultz G |title=International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 427–50 |year= 2006 |pmid= 16382100 |doi= 10.1124/pr.57.4.6
*cite journal | author=Penner R, Fleig A |title=The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7. |journal=Handb Exp Pharmacol |volume= |issue= 179 |pages= 313–28 |year= 2007 |pmid= 17217066 |doi= 10.1007/978-3-540-34891-7_19

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes