Portmanteau inhibitor

Portmanteau inhibitor

A portmanteau inhibitor is a drug which is a combination of two drug molecules, each of which is itself a type of inhibitor. The term was coined in 2007 by University of Minnesota researchers who designed and synthesized a combination HIV Reverse transcriptase inhibitor and an Integrase inhibitor.cite web|url=http://www.kare11.com/news/news_article.aspx?storyid=260376|title= U of M researchers announce advance in treatment of HIV|date=25 July 2007|accessed-date=25 July 2007] cite web|url=http://www.sciencedaily.com/releases/2007/07/070723160034.htm|title=Researchers Discover New Method To Combat HIV|date=25 July 2007|accessed-date=25 July 2007] cite journal|pmid=17608468|title=Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase|author=Zhengqiang Wang, Eric M. Bennett, Daniel J. Wilson, Christine Salomon, and Robert Vince|journal=Journal of Medicinal Chemistry|year=2007|volume=50|issue=15|url=http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/jm070512p|pages=3416–3419|doi=10.1021/jm070512p]

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