CD151

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.cite web | title = Entrez Gene: CD151 CD151 molecule (Raph blood group)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=977| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.cite web | title = Entrez Gene: CD151 CD151 molecule (Raph blood group)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=977| accessdate = ]

ee also

* Cluster of differentiation
* Tetraspanin

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye. |journal=J. Cell. Sci. |volume=114 |issue= Pt 23 |pages= 4143–51 |year= 2002 |pmid= 11739647 |doi=
*cite journal | author=Ashman LK |title=CD151. |journal=J. Biol. Regul. Homeost. Agents |volume=16 |issue= 3 |pages= 223–6 |year= 2003 |pmid= 12456024 |doi=
*cite journal | author=Ashman LK, Aylett GW, Mehrabani PA, "et al." |title=The murine monoclonal antibody, 14A2.H1, identifies a novel platelet surface antigen. |journal=Br. J. Haematol. |volume=79 |issue= 2 |pages= 263–70 |year= 1992 |pmid= 1958484 |doi=
*cite journal | author=Fitter S, Tetaz TJ, Berndt MC, Ashman LK |title=Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3. |journal=Blood |volume=86 |issue= 4 |pages= 1348–55 |year= 1995 |pmid= 7632941 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hasegawa H, Utsunomiya Y, Kishimoto K, "et al." |title=SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily. |journal=J. Virol. |volume=70 |issue= 5 |pages= 3258–63 |year= 1996 |pmid= 8627808 |doi=
*cite journal | author=Hasegawa H, Kishimoto K, Yanagisawa K, "et al." |title=Assignment of SFA-1 (PETA-3), a member of the transmembrane 4 superfamily, to human chromosome 11p15.5 by fluorescence in situ hybridization. |journal=Genomics |volume=40 |issue= 1 |pages= 193–6 |year= 1997 |pmid= 9070943 |doi= 10.1006/geno.1996.4563
*cite journal | author=Sincock PM, Mayrhofer G, Ashman LK |title=Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin. |journal=J. Histochem. Cytochem. |volume=45 |issue= 4 |pages= 515–25 |year= 1997 |pmid= 9111230 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Fitter S, Seldin MF, Ashman LK |title=Characterisation of the mouse homologue of CD151 (PETA-3/SFA-1); genomic structure, chromosomal localisation and identification of 2 novel splice forms. |journal=Biochim. Biophys. Acta |volume=1398 |issue= 1 |pages= 75–85 |year= 1998 |pmid= 9602068 |doi=
*cite journal | author=Sincock PM, Fitter S, Parton RG, "et al." |title=PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. |journal=J. Cell. Sci. |volume=112 ( Pt 6) |issue= |pages= 833–44 |year= 1999 |pmid= 10036233 |doi=
*cite journal | author=Serru V, Le Naour F, Billard M, "et al." |title=Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions. |journal=Biochem. J. |volume=340 ( Pt 1) |issue= |pages= 103–11 |year= 1999 |pmid= 10229664 |doi=
*cite journal | author=Testa JE, Brooks PC, Lin JM, Quigley JP |title=Eukaryotic expression cloning with an antimetastatic monoclonal antibody identifies a tetraspanin (PETA-3/CD151) as an effector of human tumor cell migration and metastasis. |journal=Cancer Res. |volume=59 |issue= 15 |pages= 3812–20 |year= 1999 |pmid= 10447000 |doi=
*cite journal | author=Sterk LM, Geuijen CA, Oomen LC, "et al." |title=The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes. |journal=J. Cell Biol. |volume=149 |issue= 4 |pages= 969–82 |year= 2000 |pmid= 10811835 |doi=
*cite journal | author=Whittock NV, McLean WH |title=Genomic organization, amplification, fine mapping, and intragenic polymorphisms of the human hemidesmosomal tetraspanin CD151 gene. |journal=Biochem. Biophys. Res. Commun. |volume=281 |issue= 2 |pages= 425–30 |year= 2001 |pmid= 11181065 |doi= 10.1006/bbrc.2001.4384
*cite journal | author=Charrin S, Le Naour F, Oualid M, "et al." |title=The major CD9 and CD81 molecular partner. Identification and characterization of the complexes. |journal=J. Biol. Chem. |volume=276 |issue= 17 |pages= 14329–37 |year= 2001 |pmid= 11278880 |doi= 10.1074/jbc.M011297200
*cite journal | author=Suzuki Y, Tsunoda T, Sese J, "et al." |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.164001
*cite journal | author=Kohno M, Hasegawa H, Miyake M, "et al." |title=CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. |journal=Int. J. Cancer |volume=97 |issue= 3 |pages= 336–43 |year= 2002 |pmid= 11774285 |doi=
*cite journal | author=Zhang XA, Kazarov AR, Yang X, "et al." |title=Function of the tetraspanin CD151-alpha6beta1 integrin complex during cellular morphogenesis. |journal=Mol. Biol. Cell |volume=13 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11809818 |doi= 10.1091/mbc.01-10-0481

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes