SL1 RNA

SL1 RNA

This family represents the SL1 RNA. SL1 is commonly located in the spacer region between 5S-rRNA genes where it is involved in trans-splicing. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an intra-molecular reaction which precisely joins exons derived from separately transcribed RNAs. This mechanism of mRNA maturation has been shown to occur in a number of lower eukaryotes and is commonplace in nematodes [cite journal | last = Dassanayake | first = RS | coauthors = Chandrasekharan NV, Karunanayake EH | year = 2001 | title = Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay | journal = Gene | volume = 269 | pages = 185–193 | pmid = 11376950 | doi = 10.1016/S0378-1119(01)00438-3] .

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