TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa, also known as TAF1A, is a human gene.cite web | title = Entrez Gene: TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9015| accessdate = ]

PBB_Summary
section_title =
summary_text = Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.cite web | title = Entrez Gene: TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9015| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Comai L, Zomerdijk JC, Beckmann H, "et al." |title=Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. |journal=Science |volume=266 |issue= 5193 |pages= 1966–72 |year= 1995 |pmid= 7801123 |doi=
*cite journal | author=Rudloff U, Eberhard D, Tora L, "et al." |title=TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription. |journal=EMBO J. |volume=13 |issue= 11 |pages= 2611–6 |year= 1994 |pmid= 8013460 |doi=
*cite journal | author=Di Pietro C, Rapisarda A, Amico V, "et al." |title=Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1. |journal=Cytogenet. Cell Genet. |volume=89 |issue= 1-2 |pages= 133–6 |year= 2000 |pmid= 10894955 |doi=
*cite journal | author=Zhai W, Comai L |title=Repression of RNA polymerase I transcription by the tumor suppressor p53. |journal=Mol. Cell. Biol. |volume=20 |issue= 16 |pages= 5930–8 |year= 2000 |pmid= 10913176 |doi=
*cite journal | author=Seo SB, McNamara P, Heo S, "et al." |title=Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. |journal=Cell |volume=104 |issue= 1 |pages= 119–30 |year= 2001 |pmid= 11163245 |doi=
*cite journal | author=Miller G, Panov KI, Friedrich JK, "et al." |title=hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. |journal=EMBO J. |volume=20 |issue= 6 |pages= 1373–82 |year= 2001 |pmid= 11250903 |doi= 10.1093/emboj/20.6.1373
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Dynes JL, Xu S, Bothner S, "et al." |title=The carboxyl-terminus directs TAF(I)48 to the nucleus and nucleolus and associates with multiple nuclear import receptors. |journal=J. Biochem. |volume=135 |issue= 3 |pages= 429–38 |year= 2005 |pmid= 15113842 |doi=
*cite journal | author=Yamamoto K, Yamamoto M, Hanada K, "et al." |title=Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription. |journal=Mol. Cell. Biol. |volume=24 |issue= 14 |pages= 6338–49 |year= 2004 |pmid= 15226435 |doi= 10.1128/MCB.24.14.6338-6349.2004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Grandori C, Gomez-Roman N, Felton-Edkins ZA, "et al." |title=c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. |journal=Nat. Cell Biol. |volume=7 |issue= 3 |pages= 311–8 |year= 2005 |pmid= 15723054 |doi= 10.1038/ncb1224
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes