Antigenic escape

Antigenic escape

Antigenic escape occurs when the immune system is unable to respond to an infectious agent. Antigenic escape is the end result of Antigenic variation.

One cause of Antigenic escape is that a pathogen's epitopes (the binding sites for immune cells) become too similar to a patient's naturally occurring MHC-1 epitopes. The immune system becomes unable to distinguish the infection from self-cells.

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Antigenic variation — is the process by which an infectious organism alters its surface proteins in order to evade a host immune response. This change in antigenic profile may occur as the pathogen passes through a host population (also called antigenic diversity ) or …   Wikipedia

  • Antigenic drift — Antigenic driftcite journal author=D. J. D. Earn, J. Dushoff, S. A. Levin journal=Trends in Ecology and Evolution title=Ecology and Evolution of the Flu date=2002 volume=17 pages=334 340] [cite book author=A. W. Hampson chapter=Influenza virus… …   Wikipedia

  • antigenic variation — The phenomenon of changes in surface antigens in parasitic populations of Trypanosoma and Plasmodium (and some other parasitic protozoa) in order to escape immunological defence mechanisms. At least 100 different surface proteins have been found… …   Dictionary of molecular biology

  • antigenic variation — 1. a mechanism whereby microorganisms or parasites, such as trypanosomes, plasmodia, and Borrelia, are enabled to escape immune surveillance of a host by modifying or completely altering their surface antigens. 2. a phenomenon occurring in the… …   Medical dictionary

  • Original antigenic sin — Original antigenic sin, also known as the Hoskins effect,[1] refers to the propensity of the body s immune system to preferentially utilize immunological memory based on a previous infection when a second slightly different version, of that… …   Wikipedia

  • Orthomyxoviridae — Virus classification Group: Group V (( )ssRNA) Order: Unassigned Family: Orthomyxoviridae …   Wikipedia

  • Virus — This article is about the biological agent. For other uses, see Virus (disambiguation). For a generally accessible and less technical introduction to the topic, see Introduction to viruses. Viruses …   Wikipedia

  • immune system — Anat. a diffuse, complex network of interacting cells, cell products, and cell forming tissues that protects the body from pathogens and other foreign substances, destroys infected and malignant cells, and removes cellular debris: the system… …   Universalium

  • drug — drug1 /drug/, n., v., drugged, drugging. n. 1. Pharm. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well being. 2. (in federal law) a. any substance… …   Universalium

  • Drug — /droog/, n. Zoroastrianism. the cosmic principle of disorder and falsehood. Cf. Asha. [ < Avestan drauga] * * * I Any chemical agent that affects the function of living things. Some, including antibiotics, stimulants, tranquilizers,… …   Universalium

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”