Caspase 5

Caspase 5

protein
Name = caspase 5, apoptosis-related cysteine peptidase
caption =


width = 240px
HGNCid = 1506
Symbol = CASP5
AltSymbols = ICE(rel)III, ICH3
EntrezGene = 838
OMIM = 602665
RefSeq = NM_004347
UniProt = P51878
PDB =
ECnumber = 3.4.22.58
Chromosome = 11
Arm = q
Band = 22.2-q22.3
LocusSupplementaryData =

Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system. [cite journal |author=Martinon F, Tschopp J |title=Inflammatory caspases and inflammasomes: master switches of inflammation |journal=Cell Death Differ. |volume=14 |issue=1 |pages=10–22 |year=2007 |pmid=16977329 |doi=10.1038/sj.cdd.4402038]

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