Caspase 7

Caspase-7, apoptosis-related cysteine peptidase, also known as CASP7, is a human protein and gene.

PBB_Summary
section_title =
summary_text = Caspase-7 is a member of the caspase (cysteine aspartate protase) family of proteins, and has been shown to be an executioner protein of apoptosis. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing by upstream caspases (caspase-8, -9)at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme in the form of a heterotetramer. The precursor of this caspase is cleaved by caspase 3, caspase 10, and caspase 9. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [cite web | title = Entrez Gene: CASP7 caspase 7, apoptosis-related cysteine peptidase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=840| accessdate = ]

References

Further reading

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = no
update_citations = yes

Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

Caspase-9 — Caspase 9, apoptosis related cysteine peptidase PDB rendering based on 1jxq … Wikipedia
Caspase 2 — is an enzyme that proteolytically cleaves other proteins.It belongs to a family of cysteine proteases called caspases that only cleave proteins at an amino acid following a aspartic acid residue. Within this family, caspase 2 is part of the Ich 1 … Wikipedia
Caspase 10 — Caspase 10, apoptosis related cysteine peptidase, also known as CASP10, is a human gene. PBB Summary section title = summary text = This gene encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential… … Wikipedia
Caspase 6 — Caspase 6, apoptosis related cysteine peptidase, also known as CASP6, is a human gene. PBB Summary section title = summary text = This gene encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential… … Wikipedia
Caspase 13 — is an enzyme known as a cysteine protease that was identified in cattle that is also called Evolutionarily Related Interleukin 1β Converting Enzyme (ERICE). It belongs to a family of enzymes called caspases that cleave their substrates at C… … Wikipedia
Caspase 1 — is an enzyme that proteolytically cleaves other proteins, such as the precursor forms of the inflammatory cytokines interleukin 1 β and interleukin 18, into active mature peptides. [cite journal |author=Thornberry N, Bull H, Calaycay J, Chapman K … Wikipedia
Caspase 3 — is a caspase protein. It interacts with caspase 8. PBB Summary section title = summary text = This gene encodes a protein that is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central… … Wikipedia
Caspase 8 — is a caspase protein. It most likely acts upon caspase 3. PBB Summary section title = summary text = This gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the … Wikipedia
Caspase — Caspases, or c ysteine asp artic acid prote ases , are a family of cysteine proteases, which play essential roles in apoptosis (programmed cell death), necrosis and inflammation. Caspases are essential in cells for apoptosis, one of the main… … Wikipedia
Caspase 12 — protein Name = caspase 12 caption = width = 240px HGNCid = 19004 Symbol = CASP12 AltSymbols = CASP12P1 EntrezGene = 120329 OMIM = 608633 RefSeq = NR 000035 UniProt = Q6UXS9 PDB = ECnumber = Chromosome = 11 Arm = q Band = 22.3… … Wikipedia

Academic Dictionaries and Encyclopedias

Caspase 7

Look at other dictionaries:

Share the article and excerpts

Academic Dictionaries and Encyclopedias

Wikipedia

Caspase 7

Look at other dictionaries:

Share the article and excerpts

Direct link