Psammoma body

Psammoma body

A psammoma body is a round collection of calcium, seen microscopically. The term is derived from the Greek word "psammos" meaning "sand."

Psammoma bodies are commonly seen in certain tumors such as:
* papillary thyroid carcinoma
* renal cell carcinoma
* serous ovarian adenocarcinoma (cystadenocarcinoma)
* endometrial adenocarcinomas(Papillary serous carcinoma ~3%-4%)
* meningioma
* mesothelioma

Psammoma bodies usually have a laminar appearance.

The origin of psammoma bodies is controversial, but one theory is that the nidus for their formation is a single necrotic tumor cell, upon which layers upon layers of calcium salt deposits are added.

External links

Slides:
* [http://bl-msci-007c.ads.iu.edu/c602web/602/c602web/cns/sl38_1.htm Meningioma]
* [http://cpmcnet.columbia.edu/dept/thyroid/papillary.html Thyroid cancer]
* [http://www.memfert.com/laels91/laels%2038.jpgEndometriosis (peritoneum)]
* [http://www.youtube.com/watch?v=ddEB5ITx2fw Video of psammoma bodies in meningioma]


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