Monoiodotyrosine

Monoiodotyrosine
Monoiodotyrosine
Identifiers
CAS number 29592-76-5
PubChem 3032857
MeSH Monoiodotyrosine
Properties
Molecular formula C9H10INO3
Molar mass 307.085 g/mol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Monoiodotyrosine is a precursor of thyroid hormone and results from iodization of tyrosine at the meta- position of the phenol ring.

Two units can combine to form 3,3'-diiodothyronine. One unit can combine with diiodotyrosine to form triiodothyronine, as occurs in the colloid of the thyroid follicle.

It is abbreviated "MIT".[1]

References

  1. ^ Tietze F, Kohn LD, Kohn AD, et al (March 1989). "Carrier-mediated transport of monoiodotyrosine out of thyroid cell lysosomes". J. Biol. Chem. 264 (9): 4762–5. PMID 2925666. http://www.jbc.org/cgi/pmidlookup?view=long&pmid=2925666. 



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  • monoiodotyrosine — An intermediate in thyroid hormone synthesis. * * * mono·iodo·ty·ro·sine ī .ōd ə tī rə .sēn, ī .äd ə n an iodinated tyrosine C9H10INO3 that is produced in the thyroid gland by the substitution of one iodine atom in the amino acid for an atom of… …   Medical dictionary

  • monoiodotyrosine — n. an iodine containing substance produced in the thyroid gland from which the thyroid hormones are derived …   The new mediacal dictionary

  • MIT — Monoiodotyrosine (Monoyodotirosina) …   Diccionario de siglas médicas y otras abreviaturas

  • Diiodotyrosine — Identifiers CAS number 66 02 4 …   Wikipedia

  • MIT — Abbreviation for monoiodotyrosine. * * * magnetic induction tomography; male impotence test; marrow iron turnover; Massachusetts Institute of Technology; mean input time; melodic intonation therapy; metabolism inhibition test; mira cidial… …   Medical dictionary

  • diiodotyrosine — An intermediate in the biosynthesis of thyroid hormone. * * * di·io·do·ty·ro·sine tī rə .sēn n an iodinated tyrosine C9H9I2NO3 that is produced in the thyroid gland from monoiodotyrosine and that combines with monoiodotyrosine to form… …   Medical dictionary

  • Triiodothyronine — Chembox new ImageFile = Triiodothyronine.svg ImageSize = 250px ImageFile1 = T3 3D balls.png ImageSize1 = IUPACName = (2S) 2 amino 3 [4 (4 hydroxy 3 iodo phenoxy) 3,5 diiodo phenyl] propanoic acid OtherNames = triiodothyronine T3 3,3 ,5 triiodo L… …   Wikipedia

  • Thyroglobulin — (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. In earlier literature, Tg was referred to as colloid . Thyroglobulin should not be confused with Thyroxine binding globulin, a carrier protein responsible… …   Wikipedia

  • MIT (disambiguation) — MIT commonly refers the Massachusetts Institute of Technology, an American university. MIT may also refer to: Institutes of Technology Machakos Institute of Technology, a college in Machakos, Kenya Madras Institute of Technology Chromepet, an… …   Wikipedia

  • Metabolic intermediate — Metabolic intermediates refers to molecules which are the precursors or metabolites of biologically significant molecules. Although these intermediates are of relatively minor direct importance to cellular function, they can play important roles… …   Wikipedia

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