Desmolase

Desmolase

Desmolase is an enzyme that catalyzes the formation or destruction of carbon-carbon bonds within a molecule. This enzyme plays a significant role in respiration and fermentation.

Desmolases are a group enzymes involved in steroidogenesis. Examples are:

  • Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone.
  • 17,20 desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17-hydroxypregnenolone, progesterone to 17-hydroxyprogesterone, and corticosterone to cortisol.

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  • desmolase — [dɛsmɔlɑz] n. f. ÉTYM. V. 1960 (in Manuila); du rad. du lat. sc. desmolysis (→ Desmolyse), et suff. ase. ❖ ♦ Biochim. Enzyme qui catalyse la réaction de rupture d une chaîne carbonée (→ Desmolyse) …   Encyclopédie Universelle

  • Desmolase — Des|mo|la|se [↑ Desmolyse u. ↑ ase], die; , n: veraltete Bez. für ein C C Bindungen spaltendes Enzym …   Universal-Lexikon

  • desmolase — des·mo·lase dez mə .lās, .lāz n an enzyme (as aldolase) capable of breaking or forming a carbon to carbon bond in a molecule and playing a role in respiration and fermentation * * * des·mo·lase (dezґmo lās) a nonspecific term for an enzyme… …   Medical dictionary

  • Desmolase — Desmo|la̱se [Kurzbildung aus ↑Desmolyse u. ↑...ase] w; , n: Enzym, das den Abbau des Kohlenstoffgerüstes (Spaltung von C C Verbindungen) bewirkt …   Das Wörterbuch medizinischer Fachausdrücke

  • Desmolase — Des|mo|la|se die; , n <verkürzt aus Desmolyse u. ↑...ase> veraltete Bez. für ein ↑Enzym, das die Bindung zwischen zwei Kohlenstoffatomen einer C Kette aufspaltet (Chem.) …   Das große Fremdwörterbuch

  • desmolase — n. type of enzyme that breaks down carbon …   English contemporary dictionary

  • desmolase — des·mo·lase …   English syllables

  • desmolase — ˈdezməˌlās, āz noun ( s) Etymology: New Latin desmolysis + English ase : an enzyme (as aldolase) capable of breaking or forming a carbon to carbon bond in a molecule and playing a role in respiration and fermentation often distinguished from… …   Useful english dictionary

  • cholesterol desmolase — cho·les·ter·ol des·mo·lase (kə lesґtər ol desґmol ās) cholesterol monooxygenase (side chain cleaving) …   Medical dictionary

  • 1720-desmolase — 17α hydroxyprogesterone aldolase …   Medical dictionary

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