Bismuth subgallate

Bismuth subgallate

Systematic (IUPAC) name
2,7-dihydroxy-1,3,2-benzodioxabismole-5-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	OTC (US)
Identifiers
CAS number	99-26-3 N
ATC code	A07BB
PubChem	CID 16682999
ChemSpider	10607905 Y
UNII	YIW503MI7V N
ChEBI	CHEBI:31292 Y
Chemical data
Formula	C7H5BiO6
Mol. mass	394.091 g·mol−1
SMILES	eMolecules & PubChem
InChI InChI=1S/C7H6O5.Bi.H2O/c8-4-1-3(7(11)12)2-5(9)6(4)10;;/h1-2,8-10H,(H,11,12);;1H2/q;+3;/p-3 Y Key:JAONZGLTYYUPCT-UHFFFAOYSA-K Y
Physical data
Density	1.1 g/cm³
N(what is this?)  subgallate (verify)

Bismuth subgallate, with a chemical formula C₇H₅BiO₆, is the active ingredient in Devrom (internal deodorant), an over-the-counter FDA-approved medicine commonly used to treat malodor by deodorizing flatulence and stool. Also, it has been used to treat Helicobacter pylori infection and is used in wound therapy. As an internal deodorant, it is commonly used by individuals who have had ostomy surgery, bariatric surgery, fecal incontinence, and irritable bowel syndrome.^[1]

It can cause darkening of the tongue and stools, which is temporary and harmless. A reversible encephalopathy was noted and examined in a few subjects taking bismuth subgallate.^[2]

Safety

It is quite nontoxic, but it may cause minor irritation.

See also

• Bismuth
• Gallic acid

External links

• American Cancer Society: Ileostomy Guide [1]
• Cleveland Clinic-Having an Ileostomy– A Primer for New Ostomates [2]
• United Ostomy Association of America-Ileostomy Guide [3]
• The Ostomy Files:The Issue of Oral Medications and a Fecal Ostomy [4]
• Devrom website [5]

References

1. ^ Gorbach S. L. (1990). "Bismuth therapy in gastrointestinal diseases". Gastroenterology 99 (3): 863–75. PMID 2199292. 
2. ^ Burns R., Thomas D. W., Barron V. J. (1974). "Reversible encephalopathy possibly associated with bismuth subgallate ingestion". British Medical Journal 9 (1): 220–3. PMC 1633100. PMID 4818163. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1633100.