- Perfluorooctanesulfonic acid
Chembox new
Name = Perfluorooctanesulfonic acid
ImageFile = Perfluorooctanesulfonic acid.png
ImageName =
OtherNames =
Section1 = Chembox Identifiers
CASNo = 1763-23-1
SMILES = OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Section2 = Chembox Properties
Formula = C8HF17O3S
MolarMass = 500.13 g/mol
Density =
Solvent =
SolubleOther =
MeltingPt =
BoilingPt = 133 °C at 6 Torr
Section3 = Chembox Hazards
EUClass = Corrosive (C)
RPhrases = R34Perfluorooctanesulfonic acid is an
organofluorine compound. Salts of this compound are often used assurfactant s. Like other fluorocarbons the C8F17 subunit in this compound repels water, and thesulfonic acid group makes the anion polar.Uses
Perfluorooctanesulfonic acid is usually used as the sodium or potassium
salt s, referred to as perfluorooctanesulfonates (PFOS).*PFOS was a key ingredient in
Scotchgard , a fabric protector made by3M , and numerous stain repellents. In 2000, 3M decided to reformulate Scotchgard, an effort which was finished in 2002.
*PFOS, together with PFOA, has also been used to make "aqueous film forming foam" (AFFF), a component of fire-fighting foams, andalcohol-type concentrate foam s.
*PFOS compounds can be also found in some impregnation agents for textiles, paper, and leather; in wax, polishes, paints, varnishes, and cleaning products for general use; in metal surfaces, and carpets.
*In thesemiconductor industry, PFOS is used in multiplephotolithographic chemicals including: photoacid generators (PAGs) and anti-reflective coatings (ARCs). Phased out in the European Union semiconductor industry due to health concerns.afety
Perfluorooctanesulfonates are
persistent organic pollutant s. It is exceptionally stable in the environment. In 1997, low levels of PFOS were found in tissues ofpolar bear s,dolphin s,albatross es, and blood samples from people worldwide. PFOS is considered toxic through experiments done on rats. [cite journal | author = C. Lau, J. R. Thibodeaux, R. G. Hanson, J. M. Rogers, B. E. Grey, M. E. Stanton, J. L. Butenhoff and L. A. Stevenson | title = Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation | year = 2003 | journal =Toxicol. Sci. | volume = 74 | issue = 2 | pages = 382–392 | doi = 10.1093/toxsci/kfg122 | pmid = 12773772]PFOS was detected in the bodies of almost all people tested for it in a study by the U.S. government. Studies have found that animals exposed to PFOS in levels comparable to those commonly seen in humans have altered immune function.cite journal |author=Betts KS |title=Not immune to PFOS effects? |journal=Environ. Health Perspect. |volume=116 |issue=7 |pages=A290 |year=2008 |month=July |pmid=18629339 |pmc=2453185 |doi= |url=] [Peden-Adams MM, Keller JM, Eudaly JG, Berger J, Gilkeson GS, Keil DE: "Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate". Toxicol Sci. 2008 Jul;104(1):144-54. Epub 2008 Mar 20. PMID 18359764]
ee also
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Perfluorooctanoic acid References
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External links
* [http://www.defra.gov.uk/environment/chemicals/pdf/pfos-riskstrategy.pdf PFOS risk assessment report]
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* [http://www.oecd.org/document/58/0,3343,en_2649_34375_2384378_1_1_1_1,00&&en-USS_01DBC.html OECD Hazard Assessment]
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