Platelet alpha-granule

Platelet alpha-granule

In platelets, the term "alpha granules" is used to describe granules containing several growth factors (such as insulin-like growth factor 1, platelet-derived growth factor, TGFβ), platelet factor 4 which is a heparin-binding chemokine,) and other clotting proteins (such as thrombospondin and fibronectin and von Willebrand factor). The alpha granules express the adhesion molecule P-selectin. The other type of granules within platelets are called dense granules. A deficiency of alpha granules is known as grey platelet syndrome.

ee also

* Dense granule

External links

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