Sodium aurothiomalate

Sodium aurothiomalate

drugbox
IUPAC_name = Gold(I) 2-sulfidobutanedioate


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CAS_number =
CAS_supplemental =
ATC_prefix = M01
ATC_suffix = CB02
ATC_supplemental=
PubChem = 4479093
DrugBank =
C=4 | H=3 | Au=1 | Na=1 | O=4 | S=1
molecular_weight = 344.097 g/mol
bioavailability = 0%
protein_bound =
metabolism =
elimination_half-life =
excretion =
licence_EU =
licence_US =
pregnancy_AU =
pregnancy_US =
pregnancy_category =
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legal_CA =
legal_UK = POM
legal_US =
legal_status =
dependency_liability =
routes_of_administration = intramuscular injection

Sodium aurothiomalate (gold sodium thiomalate) is an organogold compound with the chemical formula C4H3AuNaO4S and is used for its antirheumatic effects to treat rheumatoid arthritis. In the United Kingdom only this intramuscular injection drug (marketed as Myocrisin) and the orally taken Auranofin are used medically.

In popular culture

This compound appeared in the "House, M.D." episode “Clueless,” wherein it was used by a patient’s wife to poison him.

ee also

* Auranofin
* Aurothioglucose
* Disodium aurothiomalate


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Look at other dictionaries:

  • sodium aurothiomalate — INN for gold sodium thiomalate; see under gold …   Medical dictionary

  • sodium — A metallic element, atomic no. 11, atomic wt. 22.989768; an alkali metal oxidizing readily in air or water; its salts are found in natural biologic systems and are extensively used in medicine and industry. The s. ion is the most plentiful… …   Medical dictionary

  • Disodium aurothiomalate — Clinical data Pregnancy cat.  ? Legal status  ? Routes …   Wikipedia

  • gold sodium thiomalate — gold sodium thio·ma·late .thī ō mal .āt, mā .lāt n a mixture of two gold salts C4H3AuNa2O4S and C4H4AuNaO4S injected intramuscularly esp. in the treatment of rheumatoid arthritis called also gold thiomalate see MYOCHRYSINE * * * [USP] a… …   Medical dictionary

  • Gold salts — Sodium aurothiomalate …   Wikipedia

  • gold — A yellow metallic element, atomic no. 79, atomic wt. 196.96654; 198Au (half life of 2.694 days) is used in the treatment of certain tumors, for radiation synovectomy, and in imaging. SYN: aurum. cohesive g. nearly …   Medical dictionary

  • Disease-modifying antirheumatic drug — Methotrexate Hydroxychloro …   Wikipedia

  • Aurothioglucose — drugbox IUPAC name = gold(I) (2 S ,3 S ,4 R ,5 S ) 3,4,5 trihydroxy 6 (hydroxymethyl) oxane 2 thiolate width = 250 width2 = 250 CAS number = 12192 57 3 CAS supplemental = ATC prefix=M01 ATC suffix=CB04 ATC supplemental= PubChem = 6104 DrugBank =… …   Wikipedia

  • Auranofin — drugbox IUPAC name = gold(+1) cation; 3,4,5 triacetyloxy 6 (acetyloxymethyl) oxane 2 thiolate; triethylphosphanium CAS number = 34031 32 8 ATC prefix = M01 ATC suffix = CB03 ATC supplemental = PubChem = 6333901 DrugBank = APRD00808 C=20 | H=35 |… …   Wikipedia

  • Methotrexate — Amethopterin redirects here. Not to be confused with aminopterin. Methotrexate Systematic ( …   Wikipedia

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