- Submucosa
Infobox Anatomy
Name = PAGENAME
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Caption = LAYERS:
serosa
longitudinal muscle
myenteric plexus
circular muscle
submucosal plexus
submucosal
mucosal
Caption2 = Endoscopy and radialendoscopic ultrasound images of submucosal tumour in mid-esophagus . The submucosa is seen as a dark ring on the ultrasound image.
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DorlandsPre = s_27
DorlandsSuf = 12765896In the
gastrointestinal tract , the submucosa is the layer ofloose connective tissue that supports themucosa , as well as joins the mucosa to the bulk of underlyingsmooth muscle (fibers running circularly within layer of longitudinal muscle).Contents
Blood vessels ,lymphatic vessels , andnerves (all supplying the mucosa) will run through here.Tiny
parasympathetic ganglia are scattered around forming thesubmucosal plexus (or "Meissner's plexus") wherepreganglionic parasympathetic neurons synapse withpostganglionic nerve fibers that supply themuscularis mucosae .The submucosa in endoscopy
Identification of the submucosa plays an important role in diagnostic and therapeutic
endoscopy , where special fibre-optic cameras are used to perform procedures on thegastrointestinal tract . Abnormalities of the submucosa, such asgastrointestinal stromal tumor s, usually show integrity of the mucosalsurface .The submucosa is also identified in
endoscopic ultrasound to identify the depth of tumours and to identify other abnormalities. An injection ofdye ,saline , orepinephrine into the submucosa is imperative in the safe removal of certain polyps.Endoscopic mucosal
resection involves removal of the mucosal layer, and in order to be done safely, a submucosal injection of dye is performed to ensure integrity at the beginning of the procedure.ee also
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Small intestinal submucosa
=AdditionalExternal links
* - "Mammal, whole system (LM, Low)"
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* - "Tissues, Layers, and Organs: transverse section of rat gut"
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* - "Duodenum and Jejunum"
* [http://courseweb.edteched.uottawa.ca/medicine-histology/English/Gastrointestinal/Stomach22.htm Histology at edteched.uottawa.ca]
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