Enterostatin

Enterostatin is a pentapeptide produced from exocrine pancreas and gastrointestinal tract that selectively reduces fat intake.cite book
last =Fernstrom, etc
first =
authorlink =
coauthors =John D. Fernstrom, Ricardo Uauy, Pedro Arroyo
title =Nutrition and Brain: 5th Nestle Nutrition Workshop, Mexico City,
publisher =Karger Publishers
date =2000
location =
pages =Page 76
url =http://books.google.com/books?id=cvk76-ZpmSEC&pg=PA76&dq=Enterostatin&client=firefox-a&sig=ACfU3U3hzzvCPBgoG_4SyHQxMJRQVjn-AA
doi =
id = ISBN:3805571666 ] Its effects include a reduction of insulin secretion, an increase in sympathetic drive to brown adipose tissue, and the stimulation of adrenal corticosteroid secretion. At the end level, it initiates a sensation of fullness of stomach which could be the reason for its role in regulation of fat intake and reduction of body weight.

Enterostatin is a penta peptide derived from a proenzyme in the gastrointestinal tract called procolipase. It reduces food intake, in particular fat intake, when given peripherally or into the brain. [ Erlanson-Albertsson, C, York, D. Enterostatin a peptide regulating fat intake. Obes Res 1997; 5:360. ]

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