Transmetalation

Transmetalation

Transmetalation (alt. spelling: transmetallation) is a general chemical reaction type in organometallic chemistry describing the exchange of ligands between two metal centers.

The metal centers need not be the same. The ligands R and R' can be organic or inorganic. The double displacement reaction is conceptually related.

Transmetalation is important in the synthesis of various organometallic compounds. Silver "N"-heterocyclic carbene complexes are easily formed, and are often used to transfer the carbene ligands to other metals containing labile ligands such as acetonitrile or 1,5-cyclooctadiene. [cite journal | author = Wang, H. M. J., Lin, I. J. B. | title = Facile Synthesis of Silver(I)-Carbene Complexes. Useful Carbene Transfer Agents | journal = Organometallics | date = 1998 | volume = 17 | issue = 5 | pages = 972–975 | doi = 10.1021/om9709704] Where L-H+ denotes the ligand precursor:

:2 L-H+ + Ag2O → L2Ag+...AgX- (X = ligand precursor counteranion)

:L-Ag...AgX + PdCl2MeCN2 → PdL2Cl2

This reaction type also appears frequently in the catalytic cycle of various metal catalysed organic reactions such as the Stille reaction and the Negishi coupling.

References


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