Factor XIII deficiency

Factor XIII deficiency

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 31412
ICD10 = ICD10|D|68|2|d|65
ICD9 = ICD9|286.3
ICDO =
OMIM = 134570
OMIM_mult = OMIM2|134580 | MedlinePlus =
eMedicineSubj = ped
eMedicineTopic = 3040
MeshID = D005177

Factor XIII deficiency may occur very rarely, and can cause a severe bleeding tendency. Incidence is 1 in a million to 1 in 5 million people. Most are due to mutations in the A subunit. Administration of recombinant A subunit improves clot stability and may become a therapeutic option for patients with this condition [cite journal | author = Lovejoy A, Reynolds T, Visich J, Butine M, Young G, Belvedere M, Blain R, Pederson S, Ishak L, Nugent D | title = Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency. | journal = Blood | volume = 108 | issue = 1 | pages = 57–62 | year = 2006 | pmid = 16556896 | doi = 10.1182/blood-2005-02-0788] .

ee also

* Factor XIII

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Factor XIII — protein Name = coagulation factor XIII, A1 polypeptide caption = width = HGNCid = 3531 Symbol = F13A1 AltSymbols = F13A EntrezGene = 2162 OMIM = 134570 RefSeq = NM 000129 UniProt = P00488 PDB = ECnumber = Chromosome = 6 Arm = p Band = 24… …   Wikipedia

  • Coagulation factor XIII, A1 polypeptide — PDB rendering based on 1evu …   Wikipedia

  • Factor X — For other uses, see Factor X (disambiguation). Coagulation factor X PDB rendering based on 1c5m …   Wikipedia

  • Factor XI — Coagulation factor XI PDB rendering based on 1xx9 …   Wikipedia

  • Factor V — This article is about the blood coagulation protein. For the software company, see Factor 5. Coagulation factor V (proaccelerin, labile factor) PDB rendering based on 1czs …   Wikipedia

  • Factor XII — Coagulation factor XII (Hageman factor) Identifiers Symbols F12; HAE3; HAEX; HAF External IDs …   Wikipedia

  • Factor IX — Coagulation factor IX PDB rendering based on 1pfx …   Wikipedia

  • Factor VII — Coagulation factor VII (serum prothrombin conversion accelerator) Anchoring of coagulation factor VIIa to the membrane through its Gla domain …   Wikipedia

  • Factor VIII — Coagulation factor VIII, procoagulant component PDB rendering based on 1d7p …   Wikipedia

  • cryoprecipitated antihemophilic factor — [USP] a sterile, frozen concentrate of antihemophilic factor prepared from the coagulation factor VIII–rich cryoprotein fraction of human venous plasma; used for autologous replacement of factor VIII in patients with hemophilia A and for the… …   Medical dictionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”