Conserved domains

Conserved domains

Conserved domains are recurring units in polypeptide chains (sequence and structure motifs), determined and classified by comparative analysis. Molecular evolution uses such domains as building blocks and these may be recombined in different arrangements to make different proteins with different functions. They might include a pattern of amino acids typical of a particular catalytic site, or perhaps the binding site for a regulator of a protein.

ee also

*Protein domain

External links

* [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=handbook.section.110 "What Is a Conserved Domain?" at the National Center for Biotechnology website]


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Conserved domain database — CDD Content Description Conserved Domain Database for the functional annotation of proteins. Contact …   Wikipedia

  • KASH domains — are conserved C terminal protein regions less than 30 amino acids. KASH is an acronym for Klarsicht, ANC 1, Syne Homology. KASH domains always follow a transmembrane domain. Most proteins containing KASH domains are thought to be involved in the… …   Wikipedia

  • Protein domain — Pyruvate kinase, a protein from three domains (PDB 1pkn) A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three… …   Wikipedia

  • Morn repeat containing 1 — Identifiers Symbols MORN1; FLJ13941 External IDs MGI …   Wikipedia

  • Tetraspanin — family Tetraspanins have four transmembrane domains, two extracellular loops and contain a series of highly conserved amino acid residues. Identifiers Symbol Tetraspannin …   Wikipedia

  • Aryl hydrocarbon receptor — AHR redirects here. For other uses, see Ahr (disambiguation). Aryl hydrocarbon receptor Identifiers Symbols AHR; External IDs …   Wikipedia

  • MMP3 — Matrix metallopeptidase 3 (stromelysin 1, progelatinase) PDB rendering based on 1b3d …   Wikipedia

  • NFE2L2 — Nuclear factor (erythroid derived 2) like 2 Identifiers Symbols NFE2L2; NRF2 External IDs …   Wikipedia

  • Multiple sequence alignment — A multiple sequence alignment (MSA) is a sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. In many cases, the input set of query sequences are assumed to have an evolutionary relationship by which they… …   Wikipedia

  • Biomolecular Object Network Databank — The Biomolecular Object Network Databank (BOND) is a bioinformatics databank containing information on small molecule and protein sequences, structures and interactions. The databank integrates a number of existing databses to provide a… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”