Primary peritoneal cancer
- Primary peritoneal cancer
Infobox_Disease
Name = PAGENAME
Caption =
DiseasesDB =
ICD10 = ICD10|C|48|1|c|45-ICD10|C|48|2|c|45
ICD9 = ICD9|158
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D010534
Primary peritoneal cancer or carcinoma ("PPCa")[cite journal |author=Jaaback KS, Ludeman L, Clayton NL, Hirschowitz L |title=Primary peritoneal carcinoma in a UK cancer center: comparison with advanced ovarian carcinoma over a 5-year period |journal=Int. J. Gynecol. Cancer |volume=16 Suppl 1 |issue= |pages=123–8 |year=2006 |pmid=16515579 |doi=10.1111/j.1525-1438.2006.00474.x |url=http://dx.doi.org/10.1111/j.1525-1438.2006.00474.x] is a cancer of the cells lining the peritoneum, or abdominal cavity.]Some studies indicate that 7–20% of initially diagnosed epithelial ovarian cancers could be properly reclassified as primary peritoneal cancers.
Causes
Although the precise causes are not known, an link with certain variants of BRCA has been described.[cite web |url=http://www.dfci.harvard.edu/pat/adult/gynecologic-cancer/diseases-treated/primary-peritoneal-cancer.html |title=Gynecologic Cancer Treatment – Primary Peritoneal Cancer - Dana-Farber Cancer Institute |format= |work= |accessdate=] ]An association with vascular endothelial growth factor has been observed.[cite journal |author=Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI |title=Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study |journal=J. Clin. Oncol. |volume=25 |issue=33 |pages=5165–71 |year=2007 |month=November |pmid=18024863 |doi=10.1200/JCO.2007.11.5345 |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=18024863] ]Prognosis and treatment
Prognosis and treatment is the same as for the most common variation of ovarian cancer, which is epithelial ovarian cancer.[cite web |url=http://www.cancer.gov/clinicaltrials/ft-MAYO-MC0261 |title=New Drug Combination for Ovarian and Primary Peritoneal Cancers - National Cancer Institute |format= |work= |accessdate=] ][cite web |url=http://www.emedicine.com/med/TOPIC1795.HTM |title=eMedicine - Peritoneal Cancer : Article by Wissam Bleibel |format= |work= |accessdate=] ]Elevated albumin levels have been associated with a more favorable prognosis.[cite journal |author=Alphs HH, Zahurak ML, Bristow RE, Díaz-Montes TP |title=Predictors of surgical outcome and survival among elderly women diagnosed with ovarian and primary peritoneal cancer |journal=Gynecol. Oncol. |volume=103 |issue=3 |pages=1048–53 |year=2006 |month=December |pmid=16876237 |doi=10.1016/j.ygyno.2006.06.019 |url=http://linkinghub.elsevier.com/retrieve/pii/S0090-8258(06)00505-1] ]Mesothelioma
The cancer does involve mesothelial cells and can be medically described as mesothelioma; however, this cancer should not be confused with asbestos-related mesothelioma, which requires different treatments and has a much higher mortality rate.
References
External links
* [http://www.cancerhelp.org.uk/help/default.asp?page=6029 Description] at National Health Service (England)
* [http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_ovarian_cancer_33.asp?rnav=cri Description] at American Cancer Society
* to view Leah Dorfman's battle with Peritoneal Cancer visit...
http://home.att.net/~leahland/peritonealcancer.html
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