Coding region

Coding region

The coding region of a gene, also known as the coding sequence or CDS, is that portion of a gene's DNA or RNA, composed of exons, that codes for protein. The region is bounded nearer the 5' end by a start codon and nearer the 3' end with a stop codon. The coding region in mRNA is bounded by the five prime untranslated region and the three prime untranslated region, which are also parts of the exons. [1]

The coding region of an organism is sum total of the organism's genome that is composed of gene coding regions. [2]

Coding sequence annotation

While identification of open reading frames within a DNA sequence is straightforward, identifying coding sequences is not, because the cell translates only a subset of all open reading frames to proteins.[3] Currently CDS prediction uses sampling and sequencing of mRNA from cells, although there is still the problem of determining which parts of a given mRNA are actually translated to protein. CDS prediction is a subset of gene prediction, the latter also including prediction of DNA sequences that code not only for protein but also for other functional elements such as RNA genes and regulatory sequences.

See also


  1. ^ Twyman, Richard (1 August 2003). "Gene Structure". The Wellcome Trust. Retrieved 6 April 2003. 
  2. ^ Goto et al., Mami (April 8, 2000). Analysis of CpG Dinucleotide Frequency in Bacterial Genomes with Respect to Genomic Regions and Codon. The Fourth Annual International Conference on Computational Molecular Biology, Tokyo, Japan. Retrieved 6 April 2009. 
  3. ^ Furuno, Masaaki; Kasukawa, Takeya; Saito, Rintaro; Adachi, Jun; Suzuki, Harukazu; Baldarelli, Richard; Hayashizaki, Yoshihide; Okazaki, Yasushi (September 2011), "CDS Annotation in Full-Length cDNA Sequence", Genome Research (Cold Spring Harbor Laboratory Press) 21 (9): 1478–1487, doi:10.1101/gr.1060303,, retrieved 18 September 2011 

Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • region — 1. An often arbitrarily limited portion of the surface of the body. SEE ALSO: space, zone. 2. A portion of the body having a special nervous or vascular supply, or a part of an organ having a special …   Medical dictionary

  • Three prime untranslated region — The three prime untranslated region (3 UTR) is a particular section of messenger RNA (mRNA). It follows the coding region.An mRNA molecule codes for a protein through translation. The mRNA also contains regions that are not translated. In… …   Wikipedia

  • Five prime untranslated region — The five prime untranslated region (5 UTR), also known as the leader sequence, is a particular section of messenger RNA (mRNA) and the DNA that codes for it. It starts at the +1 position (where transcription begins) and ends just before the start …   Wikipedia

  • DVD region code — Region 1–8 redirects here. For the ITU regions, see International Telecommunication Union region. DVD Regions DVD region codes are a digital rights management technique designed to allow film distributors to control aspects of a release,… …   Wikipedia

  • Non-coding RNA — A non coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. Less frequently used synonyms are non protein coding RNA (npcRNA), non messenger RNA (nmRNA) and functional RNA (fRNA). The term small RNA (sRNA) is… …   Wikipedia

  • Long non-coding RNA — Long noncoding RNAs (long ncRNAs) are generally considered (somewhat arbitrarily) as non protein coding transcripts longer than 200 nucleotides. This limit is due to practical considerations including the separation of RNAs in common experimental …   Wikipedia

  • Distributed source coding — (DSC) is an important problem in information theory and communication. DSC problems regard the compression of multiple correlated information sources that do not communicate with each other.[1] By modeling the correlation between multiple sources …   Wikipedia

  • ONS coding system — In the United Kingdom, the Office for National Statistics maintains a series of codes to represent a wide range of geographical areas of the UK, for use in tabulating census and other statistical data. These codes are referred to as ONS codes or… …   Wikipedia

  • National Clinical Coding Qualification (UK) — The National Clinical Coding Qualification (UK) is the only nationally recognised qualification for clinical coders working in the NHS[1]. Upon passing the examination a clinical coder is able to use the Post nominal letters ACC. Contents 1… …   Wikipedia

  • Video coding — is the field in electrical engineering and computer science that deals with representation of video data, for storage and/or transmission, for both analog and digital video. Video coding is often considered to be only for natural video, it can… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”