Organic anion

Organic anion

Organic anions are chemically heterogeneous substances possessing a carbon backbone and a net negative charge. [1] Organic anions are conjugate bases of organic acids. The following table lists some of the organic anions and their conjugate acids which are substrates of the organic acid transporter (OAT) family of transmembrane proteins.


Organic Anions
 Conjugate Organic Acids
(acidic proton is shown in red)
p-aminohippurate (PAH)
Aminohippuric acid
cyclic nucleotides
Cyclic adenosine monophosphate (cAMP)


Cyclic guanosine monophosphate (cGMP)
prostaglandins
dicarboxylates alpha-ketoglutarate

References

  1. ^ Sekine T, Cha SH, Endou H (July 2000). "The multispecific organic anion transporter (OAT) family". Pflugers Arch. 440 (3): 337–50. PMID 10954321. http://link.springer.de/link/service/journals/00424/bibs/0440003/04400337.htm. 

Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Organic anion-transporting polypeptide — Organic Anion Transporter Polypeptide (OATP) family Identifiers Symbol OATP Pfam PF03137 InterPro …   Wikipedia

  • Organic anion transporter — can refer to: * SLCO1A2 * SLC22A6 * SLC22A7 * SLC22A8 * SLCO1B1 * SLCO1B3 …   Wikipedia

  • Organic anion transporter 1 — Figure 1 Schematic representation of transmembrane proteins: 1. a membrane protein with one transmembrane domain 2. a membrane protein with three transmembrane domains 3. OAT1 is believed to have twelve transmembrane domains. [1] The membrane is… …   Wikipedia

  • Organic cation transport proteins — An organic cation transport protein mediates the transport of organic cations across the cell membrane. These proteins are members of the solute carrier family, subfamily 22. This family of proteins can also transport zwitterions and anions,… …   Wikipedia

  • Organic superconductor — In physical chemistry and condensed matter physics, an organic superconductor is an organic compound which exhibits superconductivity at low temperatures. As of 2007 the highest achieved critical temperature for an organic superconductor at… …   Wikipedia

  • Anion gap — The anion gap is used to aid in the differential diagnosis of metabolic acidosis.CalculationIt is calculated by subtracting the serum concentrations of chloride and bicarbonate (anions) from the concentrations of sodium plus potassium (cations) …   Wikipedia

  • anion exchanger — noun : an anion exchange agent that can exchange its anion with the anion or anions of a solution passed through it or that can adsorb anions in the form of acids; especially : an insoluble basic synthetic organic resin usually containing amine… …   Useful english dictionary

  • anion — Synonyms and related words: acid, acidity, agent, alkali, alkalinity, alloisomer, antacid, atom, base, biochemical, cation, chemical, chemical element, chromoisomer, compound, copolymer, dimer, electrocoating, electroetching, electrogalvanization …   Moby Thesaurus

  • Organo-Anion-Transporter — Solute carrier organic anion transporter Masse/Länge Primärstruktur 640 722 Aminosäuren …   Deutsch Wikipedia

  • Nitrile anion — Nitrile anions are nitriles lacking a proton at the position α to the nitrile group. They undergo nucleophilic addition and substitution reactions with various electrophiles.[1] Although nitrile anions are functionally similar to enolates, the… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”