Nonsynonymous substitution
- Nonsynonymous substitution
-
A nonsynonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitutions which do not alter amino acid sequences. As nonsynonymous substitutions result in a biological change in the organism, they are subject to natural selection.
See also
External links
Wikimedia Foundation.
2010.
Look at other dictionaries:
nonsynonymous substitution — nonsynonymous substitution. См. смысловая замена [нуклеотида]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Substitution model — A substitution model describes the process from which a sequence of characters of a fixed size from some alphabet changes into another set of traits. For example, in cladistics, each position in the sequence might correspond to a property of a… … Wikipedia
смысловая замена [нуклеотида] — nonsynonymous substitution смысловая замена [нуклеотида]. Мутационная замена нуклеотида в кодирующей последовательности, приводящая к изменению последовательности аминокислот в соответствующем белке кодируемом продукте; из за вырожденности… … Молекулярная биология и генетика. Толковый словарь.
Ka/Ks ratio — In genetics, the Ka/Ks ratio (or ω, dN/dS), is the ratio of the rate of non synonymous substitutions (Ka) to the rate of synonymous substitutions (Ks), which can be used as an indicator of selective pressure acting on a protein coding gene.… … Wikipedia
смысловая замена [нуклеотида] — Мутационная замена нуклеотида в кодирующей последовательности, приводящая к изменению последовательности аминокислот в соответствующем белке кодируемом продукте; из за вырожденности генетического кода не каждая мутация является смысловой (см.… … Справочник технического переводчика
Genetic code — A series of codons in part of a messenger RNA (mRNA) molecule. Each codon consists of three nucleotides, usually representing a single amino acid. The nucleotides are abbreviated with the letters A, U, G and C. This is mRNA, which uses U (uracil) … Wikipedia
Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution … Wikipedia
Masatoshi Nei — Born January 2, 1931 Miyazaki Prefecture, Japan Fields molecular evolution, molecular phylogenetics … Wikipedia
Missense mutation — In genetics, a missense mutation (a type of nonsynonymous mutation) is a point mutation in which a single nucleotide is changed, resulting in a codon that codes for a different amino acid[1] (mutations that change an amino acid to a stop codon… … Wikipedia
APOA4 — Apolipoprotein A IV, also known as APOA4, is a human gene. PBB Summary section title = summary text = Apoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3 UTR of the third… … Wikipedia
