NKIRAS2

NFKB inhibitor interacting Ras-like 2
Identifiers
Symbols	NKIRAS2; DKFZp434N1526; KBRAS2; MGC74742; kappaB-Ras2
External IDs	OMIM: 604497 HomoloGene: 9738 GeneCards: NKIRAS2 Gene
Gene Ontology Molecular function • nucleotide binding • GTPase activity • GTP binding Cellular component • cellular_component • cytoplasm • membrane Biological process • GTP catabolic process • signal transduction • I-kappaB kinase/NF-kappaB cascade • small GTPase mediated signal transduction Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	28511	71966
Ensembl	ENSG00000168256	ENSMUSG00000017837
UniProt	Q9NYR9	Q9CR56
RefSeq (mRNA)	NM_001001349.2	NM_028024.2
RefSeq (protein)	NP_001001349.1	NP_082300.1
Location (UCSC)	Chr 17: 40.17 – 40.18 Mb	Chr 11: 100.48 – 100.49 Mb
PubMed search	[1]	[2]

NFKB inhibitor interacting Ras-like 2 is a protein that in humans is encoded by the NKIRAS2 gene.^[1]

References

1. ^ "Entrez Gene: NFKB inhibitor interacting Ras-like 2". http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=28511. Retrieved 2011-08-30. 

Further reading

• Tago K, Funakoshi-Tago M, Sakinawa M, et al. (2010). "KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.". J. Biol. Chem. 285 (40): 30622–33. doi:10.1074/jbc.M110.117028. PMID 20639196. 
• Fenwick C, Na SY, Voll RE, et al. (2000). "A subclass of Ras proteins that regulate the degradation of IkappaB.". Science 287 (5454): 869–73. doi:10.1126/science.287.5454.869. PMID 10657303. 
• Dieguez-Gonzalez R, Akar S, Calaza M, et al. (2009). "Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.". Ann. Rheum. Dis. 68 (4): 579–83. doi:10.1136/ard.2007.087304. PMID 18434448.