CJC-1293

CJC-1293 or Modified GRF 1-29 (sometimes modGRF 1-29), is a tetrasubstituted 29-amino acid peptide hormone, primarily functioning as a growth hormone releasing hormone (GHRH) analog with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively. These substitutions create a much more stable peptide with the substitution at position 2 to prevent DPP-IV cleavage, position 8 to reduce asparagine rearrangement or amide hydrolysis to aspartic acid, position 15 to enhance bioactivity, and position 27 to prevent methionine oxidation.

See also

• CJC-1295
• Sermorelin

This hormonal preparation article is a stub. You can help Wikipedia by expanding it.v · Categories: Peptide hormones Systemic hormonal preparation stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? ModBase ModNation Racers Look at other dictionaries: CJC-1295 — is a tetrasubstituted 30 amino acid peptide hormone, primarily functioning as a growth hormone releasing hormone (GHRH) analog. It was invented by ConjuChem, a Canadian biotechnology company. One of the advantages of CJC 1295 over traditional… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”