- Mink enteritis virus
Parvovirus Virus classification Group: Group II (ssDNA) Family: Parvoviridae Genus: Parvovirus Species: Mink enteritis virus
Mink enteritis virus (MEV) is a species of parvovirus that infects mink and causes enteritis. Like all parvoviruses, it is a small (18–26 nm), spherical virus, and has a single-stranded DNA genome. The signs and symptoms of enteritis usually appear within 4–7 days after infection. The virus replicates in the cells of the crypt epithelium in the duodenum and jejunum and, to a lesser extent the ileum, colon and caecum. The severity of the disease is directly related to necrosis of the crypt epithelium. 
Signs and symptoms
Clinical signs include anorexia, vomiting and severe diarrhoea. Stools of affected animals usually contain large quantities of mucus and intestinal casts or "plugs" composed of fibrin, mucus and dead cells from intestinal mucosa. In immature animals, anorexia and diarrhoea usually occur about four days after exposure to infectious material and persist for four to seven days. However, infections have been reported in which anorexia was followed by death in 12 to 24 hours without the occurrence of diarrhoea. Mortality of 80 percent or more is possible in newly-weaned kits. Mature mink often survive the disease after a period of sickness which may last several weeks. In addition to the overt signs a reduction of the number of leukocytes in the blood may be found in affected animals.
Treatment consists of oral rehydration therapy in addition to supportive care. Surgical removal of necrotic tissue may be necessary.
- ^ Collier, Leslie; Balows, Albert; Sussman Max (1998) Topley and Wilson's Microbiology and Microbial Infections ninth edition, Volume 1, Virology, volume editors: Mahy, Brian and Collier, Leslie. p. 268 Arnold. ISBN 0340663162
- ^ a b Reynolds HA (April 1969). "Some clinical and hematological features of virus enteritis of mink". Can. J. Comp. Med. 33 (2): 155–9. PMC 1319402. PMID 4238566. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1319402. Retrieved 2008-12-28.
- ^ Flagstad A (1977). "Feline panleukopaenia virus and mink enteritis virus. A serological study". Acta Vet. Scand. 18 (1): 1–9. PMID 66862.
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