Nitromersol

Nitromersol: Nitromersol

IUPAC name

5-Methyl-2-nitro-7-oxa-8-mercurabicyclo[4.2.0]octa-1(6),2,4-triene

Other names

Metaphen; 6-Methyl-3-nitrobenzoxamercurete; 4-Nitro-5-hydroxymercuriorthocresol

Identifiers

CAS number 133-58-4^Y

PubChem 16682935

ChemSpider 16739372

Jmol-3D images Image 1

SMILES

Cc1ccc(c2[Hg]Oc12)[N+]([O-])=O

InChI

InChI=1S/C7H6NO3.Hg/c1-5-2-3-6(8(10)11)4-7(5)9;/h2-3,9H,1H3;/q;+1/p-1
Key: UEHLXXJAWYWUGI-UHFFFAOYSA-M
InChI=1/C7H6NO3.Hg/c1-5-2-3-6(8(10)11)4-7(5)9;/h2-3,9H,1H3;/q;+1/p-1/rC7H5HgNO3/c1-4-2-3-5(9(10)11)6-7(4)12-8-6/h2-3H,1H3
Key: UEHLXXJAWYWUGI-ITKDQSLKAT

Properties

Molecular formula C₇H₅HgNO₃

Molar mass 351.71 g mol⁻¹

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Nitromersol (metaphen) is a mercury-containing organic compound containing that is primarily used as an antiseptic and disinfectant. It has no odor or taste and is stored as a brown-yellow granules or powder. Nitromersol does not irritate the skin or mucous membranes and has no impact on rubber or metallic instruments, including surgical and dental tools.^[1]

This compound is a confirmed animal carcinogen. It can emit toxic fumes of NO_x and mercury when destroyed by heat.^[2] In 1998, use of nitromersol (and other mercury-containing products) as OTC first-aid antiseptics and products for diaper rash and vaginal contraceptives, was outlawed by the FDA.^[3] Nitromersol can cause hypersensitivity reactions, but it is still in use as a preservative for vaccines and antitoxins.^[4]

References

^ Hospital formulary and compendium of useful information. Berkeley, California: University of California Press. 1941. p. 113. http://books.google.com/books?id=t7VW3PucgboC&pg=PA113. Retrieved 2011-04-08.

^ Lewis, Richard J. (2008). Hazardous chemicals desk reference. Wiley-Interscience. p. 1018. ISBN 0470180242. http://books.google.com/books?id=LkIWiNg4FGEC&pg=PA1018. Retrieved 2011-04-08.

^ Remington: the science and practice of pharmacy. Medicine Series. 1 (21st ed.). Lippincott Williams & Wilkins. 2005. p. 369. ISBN 0781746736.

^ Trevor, Anthony J.; Katzung, Bertram G.; Masters, Susan B. (2007). Katzung & Trevor's pharmacology: examination & board review. Lange Basic Science (8th ed.). McGraw-Hill Professional. p. 420. ISBN 0071488693.

Categories:
Antiseptics
Disinfectants
Organomercury compounds

Nitromersol

IUPAC name 5-Methyl-2-nitro-7-oxa-8-mercurabicyclo[4.2.0]octa-1(6),2,4-triene
Other names Metaphen; 6-Methyl-3-nitrobenzoxamercurete; 4-Nitro-5-hydroxymercuriorthocresol
Identifiers
CAS number	133-58-4^Y
PubChem	16682935
ChemSpider	16739372
Jmol-3D images	Image 1
SMILES Cc1ccc(c2[Hg]Oc12)[N+]([O-])=O
InChI InChI=1S/C7H6NO3.Hg/c1-5-2-3-6(8(10)11)4-7(5)9;/h2-3,9H,1H3;/q;+1/p-1 Key: UEHLXXJAWYWUGI-UHFFFAOYSA-M InChI=1/C7H6NO3.Hg/c1-5-2-3-6(8(10)11)4-7(5)9;/h2-3,9H,1H3;/q;+1/p-1/rC7H5HgNO3/c1-4-2-3-5(9(10)11)6-7(4)12-8-6/h2-3H,1H3 Key: UEHLXXJAWYWUGI-ITKDQSLKAT
Properties
Molecular formula	C₇H₅HgNO₃
Molar mass	351.71 g mol⁻¹
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

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Look at other dictionaries:

nitromersol — Medicamento antiséptico mercurial orgánico, poco eficaz como germicida, utilizado a veces para desinfectar instrumentos quirúrgicos y como antiséptico de piel y mucosas. Diccionario Mosby Medicina, Enfermería y Ciencias de la Salud, Ediciones… … Diccionario médico
nitromersol — /nuy treuh merr sawl, sol/, n. Chem. a brownish yellow or yellow, granular, water insoluble powder, C7H5HgNO3: used in alkaline solution chiefly as an antiseptic. [NITRO + MER(CURIC) + (CREO)SOL] * * * ▪ chemical compound synthetic mercury… … Universalium
nitromersol — The anhydride of 4 nitro 3 hydroxymercuriorthocresol; a synthetic organic mercurial compound, used as an antiseptic for skin and mucous membranes. * * * ni·tro·mer·sol mər .sȯl, .sōl n a brownish yellow to yellow solid organic mercurial… … Medical dictionary
nitromersol — n. brownish yellow powder used in alkaline solutions as a disinfectant (Chemistry) … English contemporary dictionary
nitromersol — ni·tro·mersol … English syllables
nitromersol — ˌ ̷ ̷ ̷ ̷ˈmərˌsȯl, ōl noun ( s) Etymology: nitr + mercury + cresol : a brownish yellow to yellow solid organic mercurial C7H5HgNO3 that is a derivative of ortho cresol used chiefly in the form of a solution of its sodium salt as an antiseptic… … Useful english dictionary
Metaphen — ˈmed.əfə̇n trademark used for nitromersol * * * /met euh fen /, Pharm., Trademark. a brand of nitromersol … Useful english dictionary
Thiomersal — Thiomersal … Wikipedia
Organomercury — compounds Organomercury refers to the group of organometallic compounds that contain mercury. Typically the Hg C bond is stable toward air and moisture but sensitive to light. Important organomercury compounds are the methylmercury cation,… … Wikipedia
merbromin — /meuhr broh min/, n. Pharm. an iridescent green, water soluble powder, C20H8Br2HgNa2O6, that forms a red solution when dissolved in water: used as an antiseptic and as a germicide. [1940 45; MER(CURIC) + BROM(O) + IN2] * * * ▪ antiseptic … … Universalium

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Nitromersol

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