Doxercalciferol

Doxercalciferol
IUPAC name (1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol
Other names 1-Hydroxyergocalciferol; 1-Hydroxyvitamin D2; 1α-Hydroxyergocalciferol; 1α-Hydroxyvitamin D2; Hectorol; TSA 840
Identifiers
CAS number	54573-75-0 Y
PubChem	5281107
ChemSpider	4444554 Y
UNII	3DIZ9LF5Y9 Y
Jmol-3D images	Image 1
SMILES O[C@@H]1CC(\C(=C)[C@@H](O)C1)=C\C=C2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](/C=C/[C@H](C)C(C)C)C)C
InChI InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1 Y Key: HKXBNHCUPKIYDM-CGMHZMFXSA-N Y InChI=1/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1 Key: HKXBNHCUPKIYDM-CGMHZMFXBN
Properties
Molecular formula	C28H44O2
Molar mass	412.65 g mol−1
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Doxercalciferol (trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease.^[1] It is a synthetic analog of ergocalciferol (vitamin D₂). It suppresses parathyroid synthesis and secretion.^[2]

References

1. ^ Sprague S M; Ho L T (2002). "Oral doxercalciferol therapy for secondary hyperparathyroidism in a peritoneal dialysis patient". Clinical nephrology 58 (2): 155–160. PMID 12227689. 
2. ^ "Doxercalciferol". Drugs.com. http://www.drugs.com/ppa/doxercalciferol.html. 

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Pharmacology stubs Secosteroids Diols Vitamin D Wikimedia Foundation. 2010. Игры ⚽ Поможем написать курсовую Doxastikon Doxey pool Look at other dictionaries: doxercalciferol — dox·er·cal·cif·er·ol (dok″sər kal sifґər ol) a synthetic analogue of vitamin D2, used to reduce levels of circulating parathyroid hormone in the treatment of secondary hyperparathyroidism associated with chronic renal failure;… …   Medical dictionary doxercalciferol — A substance being studied in the prevention of recurrent prostate cancer. It is a type of vitamin D analog …   English dictionary of cancer terms Vitamin D — is a group of fat soluble prohormones, the two major forms of which are vitamin D2 (or ergocalciferol) and vitamin D3 (or cholecalciferol).cite web|url=http://dietary supplements.info.nih.gov/factsheets/vitamind.asp|title=Dietary Supplement Fact… …   Wikipedia Teriparatide — Clinical data Trade names Forteo AHFS/Drugs.com …   Wikipedia List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia Cinacalcet — Systematic (IUPAC) name (R) N [1 (1 naphthyl)ethyl] 3 [3 (trifluoromethyl)phenyl]propan 1 amine Clinical data …   Wikipedia Hectorol — Hec·to·rol (hekґtə rol) trademark for preparations of doxercalciferol …   Medical dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”