Dolichyl-diphosphate—polyphosphate phosphotransferase

Dolichyl-diphosphate—polyphosphate phosphotransferase
dolichyl-diphosphate-polyphosphate phosphotransferase
Identifiers
EC number 2.7.4.20
CAS number 94949-27-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a dolichyl-diphosphate-polyphosphate phosphotransferase (EC 2.7.4.20) is an enzyme that catalyzes the chemical reaction

dolichyl diphosphate + (phosphate)n \rightleftharpoons dolichyl phosphate + (phosphate)n+1

Thus, the two substrates of this enzyme are dolichyl diphosphate and (phosphate)n, whereas its two products are dolichyl phosphate and (phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is dolichyl-diphosphate:polyphosphate phosphotransferase. This enzyme is also called dolichylpyrophosphate:polyphosphate phosphotransferase.

References

  • Naumov AV, Shabalin YA, Vagabov VM and Kulaev IS (Moscow). "Two pathways of dephosphorylation of dolichyl diphosphate in yeasts". B Biochemistry: 551–556. 
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