Broad Institute

Broad Institute

The Broad Institute of MIT and Harvard is an American research institute dedicated to the study of genomics for the biomedical sciences.


The Broad Institute evolved from a decade of research collaborations among young scientists affiliated with MIT and Harvard. [cite web
title = Broad Institute created: Links Harvard, M.I.T., and others in interdisciplinary initiative in genomics and medicine
url =
publisher = Harvard Gazette
date = 2003-07-17
accessdate = 2007-12-25

One cornerstone was the Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and human genetics.

Another cornerstone was the Institute of Chemistry and Cell Biology established by Harvard Medical School in 1998 to pursue chemical genetics as an academic discipline. [cite web
url =
title = A Brief History of the ICCB-Longwood Screening Facility
publisher = Harvard Medical School
accessdate = 2007-12-25
] Its screening facility was one of the first high-throughput resources opened in an academic setting. It facilitated small molecule screening projects for more than 80 research groups worldwide.

To create a new organization that was open, collaborative, cross-disciplinary and able to organize projects at any scale, planning took place in 2002-2003 among philanthropists Eli and Edythe Broad, MIT, the Whitehead Institute, Harvard and the Harvard hospitals (the Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Children's Hospital Boston, the Dana-Farber Cancer Institute and the Massachusetts General Hospital).

The Broads made a founding gift of $100 million and the Broad Institute was formally launched in May 2004. In November 2005, the Broads announced an additional $100 million gift to the Institute. [cite web
url =
title = Broads' Dollars Doubled
date = 2005-11-30
publisher = Broad Institute
] On 4 September 2008 the Broad's gave another $400 million to the Broad Institute. The donation will be managed by Harvard's investment unit. []

"Note: "Broad" rhymes with "toad", not "thawed"; staffers are often seen wearing tee shirts bearing the quip, "Broad as in code."

Research programs

The Broad Institute's scientific research programs include the:

* Cancer Program
* Program in Medical and Population Genetics
* Genome Biology and Cell Circuits Program
* Chemical Biology Program
* Metabolic Disease Initiative
* Infectious Disease Initiative
* Psychiatric Disease Initiative
* Computational Biology and Bioinformatics


The faculty and staff of the Broad Institute include physicians, geneticists, and molecular, chemical, and computational biologists. The Faculty currently includes six Core Members, whose labs are primarily located within the Broad Institute, and 108 Associate Members, whose primary labs are located at one of the universities or hospitals.

The Core Members of the Broad Institute currently are:

* David Altshuler, a clinical endocrinologist and human geneticist, is director of the Medical and Population Genetics program. He studies human genetic variation and its application to disease, using tools and information from the Human Genome Project.
* Todd Golub, a physician-researcher, is director of the Cancer program. He applies genomic tools to the classification and study of cancers.

* Deborah Hung is a chemical biologist and an infectious disease physician who studies the interactions between pathogens and their hosts, with the goal of discovering new antibiotic targets.

* Eric Lander is the director of the Broad Institute. A geneticist, molecular biologist and mathematician, Lander has been a driving force in the development of genomics and a prominent leader of the Human Genome Project.

* Aviv Regev is a computational biologist with interests in biological networks, gene regulation and evolution.

* Stuart Schreiber is director of the Chemical Biology program. He has developed systematic ways to explore biology, especially disease biology, using small molecules toward the development of therapeutic drugs.


The Broad Institute's facilities at 320 Charles Street in Cambridge, Massachusetts, house one of the largest genome sequencing centers in the world. As WICGR (Whitehead Institute/MIT Center for Genome Research), this facility was the largest contributor of sequence information to the Human Genome Project.

In February 2006, much of The Broad Institute relocated to a new building at 7 Cambridge Center, adjacent to the Whitehead Institute for Biomedical Research. [ [ Map of 320 Charles Street and 7 Cambridge Center, Cambridge, MA] ] This seven-story convert|231000|sqft|m2|sing=on building contains office, research laboratory, retail and museum space.


External links

* [ Official website of the Broad Institute]

Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • BROAD, ELI — (1933– ), U.S. businessman, philanthropist, art collector. The New York born only child of Lithuanian immigrants, Broad built two of the largest businesses in the United States from the ground up. He was chairman of AIG Retirement Services Inc.,… …   Encyclopedia of Judaism

  • Broad — may refer to:* Broad (British coin), English gold coin minted under the commonwealth with a bust of Oliver Cromwell on the obverse * Broad church, Latitudinarian churchmanship in the Church of England * Broad Front Progressive Encounter New… …   Wikipedia

  • Broad Based Black Economic Empowerment — (BBBEE) is a form of Black Economic Empowerment initiated by the South African government in response to criticism against Narrow Based Empowerment instituted in the country during 2003/2004. While Narrow Based Black Economic Empowerment led to… …   Wikipedia

  • Institute of Risk Management — (IRM) is a risk management professional education and training body. It was established in 1986, as a not for profit company limited by guarantee, and is governed by a Board of Directors elected from Fellows of the Institute. It has around 2000… …   Wikipedia

  • Institute of Bangladesh Studies — is a research institute in Rajshahi University, Bangladesh. Established in 1973, it is a leading research institute in the arts and social sciences. Basically, it is an advanced centre for inter disciplinary study and research on various aspects… …   Wikipedia

  • Institute of Public Enterprise — The Institute of Public Enterprise (IPE), (Hyderabad, India) is an autonomous non profit educational society established in 1964. It is devoted to management education, training, research, consultancy, IT and biotechnology for business… …   Wikipedia

  • Institute of Biosciences and Technology — The Institute of Biosciences and Technology (IBT), a component of the Texas A M Health Science Center represents the Texas A M University System, one of the two main Texas state university systems, in the state s and world s largest medical… …   Wikipedia

  • Institute of Certified Records Managers — In today s evolving knowledge economies, the convergence of IM domains indicates the need for a greater integration of management disciplines that build the capacity of business to achieve desired outcomes. Among disciplines such as Financial and …   Wikipedia

  • Institute for Pure and Applied Mathematics — The Institute for Pure and Applied Mathematics (IPAM) is an American mathematics institute funded by the National Science Foundation. The initial funding for the institute was approved in May 1999 [cite web|url =… …   Wikipedia

  • Broad Street, Oxford — [ Clarendon Building, and the Sheldonian Theatre and the Old Ashmolean Building.] Broad Street is a wide street in Oxford, England. It is famous for its bookshops, including the original Blackwell s bookshop at number 50. Locally, the street is… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”