David Callaway

David J. E. Callaway is a biological nanophysicist in the New York University School of Medicine, where he is Professor and Laboratory Director. He was trained as a theoretical physicist by Richard Feynman and Cosmas Zachos, and was previously an Associate Professor at the Rockefeller University. Recently Callaway's laboratory discovered potential new therapeutics for Alzheimer's disease based upon apomorphine.^[1] An earlier paper of his developing models of Alzheimer amyloid formation,^[2] has been cited over 177 times in the Scopus database. He has also initiated^[3] the study of protein domain dynamics by neutron spin echo spectroscopy, providing a way to observe protein nanomachines in motion.

Previous work includes the invention of the microcanonical ensemble approach to lattice gauge theory with Aneesur Rahman,^[4][5] cited over 100 times, work on the convexity of the effective potential of quantum field theory,^[6] and work on Langevin dynamics in quantum field theory with John R. Klauder.^[7] A monograph^[8] discussing Quantum triviality and whether an elementary scalar Higgs boson can exist was cited over 123 times in the HEP database. Another paper of his providing constraints on the Higgs boson^[9] has been cited over 103 times in that database as well. He has also published well-cited papers on topics including black holes, superconductors and protein chemistry.

Callaway is an avid expedition mountaineer and polar explorer.

References

1. ^ Lashuel, H. A.; Hartley, D. M.; Balakhaneh, D.; Aggarwal A.; Teichberg S.; Callaway, D. J. E. (2002). "New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease". J Biol Chem 277 (45): 42881–42890. doi:10.1074/jbc.M206593200. PMID 12167652. http://www.jbc.org/cgi/content/abstract/277/45/42881. 
2. ^ Tjernberg, L. O.; Callaway, D. J. E.; Tjernberg, A.; Hahne, S.; Lilliehöök, C.; Terenius, L.; Thyberg, J.; Nordstedt, C. (1999). "A molecular model of Alzheimer amyloid ß-peptide fibril formation". J Biol Chem 274 (18): 12619–12625. doi:10.1074/jbc.274.18.12619. PMID 10212241. http://www.jbc.org/cgi/content/full/274/18/12619. 
3. ^ Bu, Z.; Biehl, R; Monkenbusch, M.; Richter, D.; Callaway, D. J. E. (2005). "Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy.". Proc Natl Acad Sci USA 102 (49): 17646–17651. Bibcode 2005PNAS..10217646B. doi:10.1073/pnas.0503388102. PMC 1345721. PMID 16306270. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1345721. 
4. ^ D. J. E. Callaway and A. Rahman (1982). "Microcanonical Ensemble Formulation of Lattice Gauge Theory". Phys Rev Lett 49: 613–616. Bibcode 1982PhRvL..49..613C. doi:10.1103/PhysRevLett.49.613. 
5. ^ D. J. E. Callaway and A. Rahman (1983). "Lattice gauge theory in the microcanonical ensemble". Phys Rev D 28: 1506–1514. Bibcode 1983PhRvD..28.1506C. doi:10.1103/PhysRevD.28.1506. 
6. ^ D. J. E. Callaway and D. J. Maloof (1982). "Effective potential of lattice φ4 theory". Phys Rev D D27: 406–411. Bibcode 1983PhRvD..27..406C. doi:10.1103/PhysRevD.27.406. http://link.aps.org/doi/10.1103/PhysRevD.27.406. 
7. ^ D. J. E. Callaway, F. Cooper, J. R. Klauder, H. A. Rose (1985). "Langevin simulations in Minkowski space". Nuclear Physics B 262: 19–32. Bibcode 1985NuPhB.262...19C. doi:10.1016/0550-3213(85)90061-6. 
8. ^ D. J. E. Callaway (1988). "Triviality Pursuit: Can Elementary Scalar Particles Exist?". Phys. Reports 167: 241–320. Bibcode 1988PhR...167..241C. doi:10.1016/0370-1573(88)90008-7. 
9. ^ D. J. E. Callaway (1984). "Non-triviality of gauge theories with elementary scalars and upper bounds on Higgs masses". Nuclear Physics B 233: 189–203. Bibcode 1984NuPhB.233..189C. doi:10.1016/0550-3213(84)90410-3. 

External links

• web page at NYU
• Dr. Callaway's publications on the SPIRES HEP Literature Database [1]

and on the PubMed database

• [2]

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