- dCTP diphosphatase
dCTP diphosphatase Identifiers EC number 220.127.116.11 CAS number 9024-87-7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles
In enzymology, a dCTP diphosphatase (EC 18.104.22.168) is an enzyme that catalyzes the chemical reaction
- dCTP + H2O dCMP + diphosphate
Thus, the two substrates of this enzyme are dCTP and H2O, whereas its two products are dCMP and diphosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is dCTP nucleotidohydrolase. Other names in common use include deoxycytidine-triphosphatase, dCTPase, dCTP pyrophosphatase, deoxycytidine triphosphatase, deoxy-CTPase, and dCTPase. This enzyme participates in pyrimidine metabolism.
- Zimmerman SB and Kornberg A (1961). "Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Escherichia coli". J. Biol. Chem. 236: 1480–1486. PMID 13788541.
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