Cryptolepine

Cryptolepine

Systematic (IUPAC) name
5-Methyl-5H-indolo[3,2-b]quinoline
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	480-26-2
ATC code	?
PubChem	CID 82143
ChemSpider	74137
ChEMBL	CHEMBL92129
Synonyms	5-Methyl-5H-quindoline
Chemical data
Formula	C16H12N2
Mol. mass	233.3
SMILES	eMolecules & PubChem

Cryptolepine is an antimalarial drug with cytotoxic properties. It is used as an anticancer drug as it is able to intercalate into DNA at the cytosine-cytosine sites.^[1][2]

References

1. ^ "Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents". C. Wright et al. Journal of Medicinal Chemistry. 44(19). 3187-3194. 2001.
2. ^ "Synthesis of Some Cryptolepine Analogues, Assessment of Their Antimalarial and Cytotoxic Activities, and Consideration of Their Antimalarial Mode of Action". C Wright et al. Journal of Medicinal Chemistry. 48(7). 2701-2709. 2005.