Epomediol

Epomediol
Epomediol
Systematic (IUPAC) name
(1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-6,7-diol
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 56084-15-2
ATC code A05BA05
PubChem CID 115056
ChemSpider 102967
Synonyms 1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol
Chemical data
Formula C10H18O3 
Mol. mass 186.248 g/mol
SMILES eMolecules & PubChem

Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.[1][2][3]

References

  1. ^ Gonzalez MC, Iglesias J, Tiribelli C, et al. (September 1992). "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol 16 (1-2): 241–2. doi:10.1016/S0168-8278(05)80122-9. PMID 1484159. http://linkinghub.elsevier.com/retrieve/pii/S0168-8278(05)80122-9. 
  2. ^ Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am 21 (4): 905–21. PMID 1478743. 
  3. ^ Reyes H, Simon FR (August 1993). "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis 13 (3): 289–301. doi:10.1055/s-2007-1007357. PMID 8235718. 
v · d · eBile and liver therapy (A05)
Bile therapy
Liver therapy
Arginine glutamate • Silymarin • Citiolone • Epomediol • Ornithine oxoglutarate • Tidiacic arginine • Glycyrrhizin

M: DIG

anat(t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug(A2A/2B/3/4/5/6/7/14/16), blte


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