Akt/PKB signaling pathway
- Akt/PKB signaling pathway
The Akt/PKB signaling pathway is a pathway in cell signaling.[cite journal |author=Song G, Ouyang G, Bao S |title=The activation of Akt/PKB signaling pathway and cell survival |journal=J. Cell. Mol. Med. |volume=9 |issue=1 |pages=59–71 |year=2005 |pmid=15784165 |doi= |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=1582-1838&date=2005&volume=9&issue=1&spage=59] ]Proteins involved include AKT (also known as "protein kinase B") and phosphoinositide 3-kinase.
It can be associated with cancer.[cite journal |author=DeFeo-Jones D, Barnett SF, Fu S, "et al" |title=Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members |journal=Mol. Cancer Ther. |volume=4 |issue=2 |pages=271–9 |year=2005 |month=February |pmid=15713898 |doi= |url=http://mct.aacrjournals.org/cgi/pmidlookup?view=long&pmid=15713898] ]References
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