Factor Xa inhibitor

Factor Xa inhibitor

Factor Xa inhibitors are a new class of antithrombotics which act directly upon Factor X in the coagulation cascade.

Examples include Fondaparinuxcite journal |author=Weitz JI, Hirsh J, Samama MM |title=New anticoagulant drugs: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy |journal=Chest |volume=126 |issue=3 Suppl |pages=265S–286S |year=2004 |month=September |pmid=15383475 |doi=10.1378/chest.126.3_suppl.265S |url=http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=15383475] and Idraparinux.cite journal |author=Gross PL, Weitz JI |title=New anticoagulants for treatment of venous thromboembolism |journal=Arterioscler. Thromb. Vasc. Biol. |volume=28 |issue=3 |pages=380–6 |year=2008 |month=March |pmid=18296593 |doi=10.1161/ATVBAHA.108.162677 |url=http://atvb.ahajournals.org/cgi/pmidlookup?view=long&pmid=18296593]

Another example is Rivaroxaban.cite journal |author=Turpie AG |title=Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases |journal=Arterioscler. Thromb. Vasc. Biol. |volume=27 |issue=6 |pages=1238–47 |year=2007 |month=June |pmid=17379841 |doi=10.1161/ATVBAHA.107.139402 |url=http://atvb.ahajournals.org/cgi/pmidlookup?view=long&pmid=17379841]

References


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