Antistreptolysin O titre

Antistreptolysin O titre (AS(L)O titre or AS(L)OT) - titre of (serum) antistreptolysin O antibodies is a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci.

The ASOT helps direct the antimicrobial treatment and is used to assist in the diagnosis of scarlet fever, rheumatic fever and post infectious glomerulonephritis.

A positive test usually is >200 units/mL,Antistreptococcal antibody titres. gpnotebook. URL: [http://www.gpnotebook.co.uk/cache/-1630535637.htm http://www.gpnotebook.co.uk/cache/-1630535637.htm] . Accessed on: March 31, 2007.] but normal ranges vary from laboratory to laboratory and by age. [cite journal |author=Danchin M, Carlin J, Devenish W, Nolan T, Carapetis J |title=New normal ranges of antistreptolysin O and antideoxyribonuclease B titres for Australian children |journal=J Paediatr Child Health |volume=41 |issue=11 |pages=583–6 |year=2005 |pmid=16398843 |doi=10.1111/j.1440-1754.2005.00726.x]

The false negatives rate is 20-30%. If a false negative is suspected, then an anti-DNase B titre should be sought. False positives can result from liver disease and tuberculosis.

References

ee also

*List of medical abbreviations
*streptococcus

External links

* [http://www.gpnotebook.co.uk/simplepage.cfm?ID=-1630535637 Antistreptococcal antibody titres] - GPnotebook.co.uk.
* [http://www.medterms.com/script/main/art.asp?articlekey=10946 Antistreptolysin O Titer] - medterms.com.
* [http://www.ucihs.uci.edu/com/pathology/PathologyServicesManual/..%5CPathology%20Service%20Manual%5CANTISTREPTOLYSIN%20O%20TITER,%20SERUM.htm Antistreptolysin O Titer, Serum]
* [http://www.healthatoz.com/healthatoz/Atoz/ency/streptococcal_antibody_tests.jsp Streptococcal antibody tests] - healthAtoZ.com